Project Manager - Operations

Signant Health

About Signant Health
At Signant Health, we help bring life-changing treatments to patients faster. We are a global evidence generation company supporting clinical trials through smart technology, scientific expertise, and hands-on operational support — because better data leads to better healthcare decisions. Our teams work at the intersection of science, technology, and patient experience, delivering digital solutions that make clinical trials more efficient, accurate, and accessible worldwide. Trusted by leading pharmaceutical companies and CROs, our platforms and services support studies in more than 90 countries and have contributed to hundreds of new drug approvals. If you are motivated by meaningful work, global impact, and innovation in clinical research and digital health, you will find purpose — and opportunity — at Signant Health.
About The Role
The Project Manager is responsible for the end-to-end planning, execution, and delivery of projects across Signant Health’s solutions, including Advisory, eCOA, and RTSM. This role ensures alignment with project budgets, timelines, resources, and quality standards while maintaining compliance with regulatory and contractual requirements.
The Project Manager will manage the full software development lifecycle (SDLC), lead cross-functional teams, mitigate risks, and serve as the primary client contact for all project activities. This position requires an experienced, proactive leader who excels at problem-solving, motivates results-oriented teams, and builds strong, trust-based relationships with internal and external stakeholders.
What You Will Do
Manage and lead the successful delivery of multiple, concurrent projects across Advisory, eCOA, and RTSM product lines, ensuring adherence to scope, budget, timelines, and quality.
Oversee the full SDLC from requirements gathering through deployment, ensuring software and solutions are tailored to each client’s specifications.
Apply expertise in project lifecycle management, including:
Budget management and forecasting
Risk identification, mitigation, and assessment
Milestone tracking and reporting
Change management and control
Use project management tools such as Jira, MS Project, Asana, Monday, or Trello to plan, monitor, and track deliverables.
Collaborate with cross-functional teams—Product, Engineering, Quality, and Operations—to ensure compliance with quality and regulatory standards in a highly regulated (Pharma/CRO) environment.
Ensure systems are configured, tested, and deployed in line with client expectations.
Lead client communications, including regular project updates, escalation management, and change discussions.
Handle client escalations independently, collaborating across internal and client teams to resolve issues promptly.
Oversee the financial performance of assigned projects, including vendor management, device procurement, invoicing, and resource allocation.
Support the implementation of complex, multi-product or multi-country projects requiring integration of Advisory, RTSM, and eCOA solutions.
Partner with the Quality Management team to identify, document, and close incident reports in a timely manner.
Provide accurate and transparent project reporting to internal and external stakeholders.
Key Accountabilities – Strategic & Cultural Responsibilities
Promote a culture of continuous improvement, focusing on process efficiency, client value, and operational excellence.
Ensure compliance with internal procedures, client deliverables, and applicable GxP and data protection regulations.
Uphold company values centered on people, clients, and performance.
Contribute to the refinement of project delivery methodologies to improve scalability and consistency across global teams.
Decision-Making and Influence
Lead through influence, guiding cross-functional teams toward shared goals without direct authority.
Assess and manage risks effectively, making informed decisions aligned with company values and client commitments.
Resolve escalations with professionalism, accountability, and transparency.
Communicate proactively and adapt decision-making to evolving project conditions.
Preferred Qualifications
Bachelor’s degree or equivalent experience in Computer Science, Life Sciences, Project Management, or a related field.
Proven experience managing end-to-end projects in a regulated industry (Pharma, Healthcare, or CRO).
Strong understanding of the software development lifecycle (SDLC) and experience adapting technical solutions to meet client needs.
Demonstrated experience in project lifecycle management, including budget oversight, risk management, milestone tracking, and change control.
Hands-on experience with project management tools such as Jira, MS Project, Asana, Monday, or Trello.
Strong analytical, organizational, and problem-solving skills with keen attention to detail.
Excellent verbal and written communication skills, with the ability to influence and engage at all organizational levels.
Proven ability to work independently, prioritize tasks, and meet tight deadlines in dynamic, fast-paced environments.
Proficiency with MS Office Suite (Word, Excel, PowerPoint, Project).
Desired Qualifications
Background in clinical research, life sciences, or software delivery within a CRO or pharmaceutical environment.
Experience with IRT/RTSM systems, eCOA/ePRO solutions, or Advisory/Consulting engagements.
Knowledge of Good Clinical Practice (GCP), FDA, and other global regulatory requirements.
PMP, PRINCE2, or equivalent project management certification.
Strong presentation skills and ability to facilitate discussions across large, cross-functional teams.
Willingness to travel occasionally for client meetings or internal collaboration (typically quarterly).
Why Signant Health?
At Signant Health, your work has real impact. Everything we build, support, and deliver helps advance clinical research and bring new treatments to patients faster — improving lives around the world. Our teams combine science, technology, and operational expertise to solve complex clinical trial challenges, and every role contributes to that mission. We offer a collaborative, global environment where you can grow your career while working alongside experts across clinical, technology, data, and operations, with opportunities to learn, take ownership, and drive meaningful innovation — not just maintain the status quo. If you are looking for purpose-driven work, smart colleagues, and the opportunity to help shape the future of clinical research and digital health, Signant Health is the place to do it.
Language: Resumes must be submitted in English.
At Signant Health, accepting difference isn’t enough—we celebrate it, we support it, and we nurture it for the benefit of our team members, our clients and our community. Signant Health is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or veteran status.

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